21 Janvier 2021

Peur de la vaccination : où en sommes-nous de nos connaissance des effets adverses ?

(par le Dr Bernard Pradines – Gériatre, ancien anesthésiste)

https://data.over-blog-kiwi.com/4/55/63/38/20210121/ob_2afc12_covidreference06.pdf

Effets secondaires du Pfizer/BioNTech dans la revue de la littérature en référence 

Je reprends ma casquette d’expert « ponctuel » en 2020 auprès de l’ANSM

Extraits du document en fichier lié ci-dessous (revue de littérature actualisée le 8 janvier 2021)

Tous vaccins à ARNm par rapport aux autres vaccins pour toutes pathologies :

“the incidence of anaphylaxis associated with

the Pfizer SARS-CoV-2 mRNA vaccine appears to be approximately 10 times as

high as the incidence reported with all previous vaccines, at approximately 1

in 100,000, as compared to 1 in 1,000,000 (Castells 2020)”

Tozinameran = Pfizer/BioNTech

Effets indésirables non « sévères » :

Effets indésirables « sévères » :

“Sévère” n’est pas “sérieux” :

“Serious adverse events are defined as requiring hospitalization, deemed life-threatening, or resulting in persistent or significant disability/incapacity,

another medically important condition, or death. The terms serious and severe

are NOT synonymous. The general term severe is often used to describe

the intensity (severity) of a specific event; the event itself, however, may be

of relatively minor medical significance (such as a Grade 3 headache). This is

NOT the same as serious, which is based on patient/event outcome and is

usually associated with events that pose a threat to a patient’s life or ability

to function. A severe AE (Grade 3 or 4) is not necessarily serious.

Conduite à tenir selon cette source :

« In particular, persons without contraindications to vaccination

who receive an mRNA COVID-19 vaccine should be observed after vaccination

for the following time periods:

• 30 minutes: Persons with a history of an immediate allergic reaction

of any severity to a vaccine or injectable therapy and persons with a

history of anaphylaxis due to any cause.

• 15 minutes: All other persons »